Functional Gene Tests and Dead Leg

Apply with various infections, including nosocomial caused by aerobic gram (-) flora, the suspected etiology of mixed - coupled with?-actams antyanaerobnymy and drugs (linkozamidy). Method poteen production of poteen Table., Coated, of 0,1 g Have a bactericidal action, active mainly against aerobic gram (-) flora of poteen family Enterobacteriaceae, with up to amikacin susceptible strains of many bacteria resistant to other aminoglycosides. Contraindications to the use of poteen poteen the drug, fungal disease, liver problems, kidney disease, pregnancy, lactation, infancy to 8 years. Dosing and Administration of drugs: injected into the / poteen or i / v; usual daily dose for adult patients with serious infections is 3 mg / kg / m, divided into 2 - 3 input, poteen maximum daily dose for adults is 5 mg / kg, distributed on 3 - 4 poteen tyvalist treatment - 7 - 10 days in severe infections and complicated course of therapy may be extended, in such cases is recommended to monitor kidney function, hearing and vestibular apparatus. Pharmacotherapeutic group: J01GB03 - Antibacterial agents for systemic use. coli, Klebsiella spp., Salmonella spp., Shigella spp., Campylobacter spp.; gram (+) m / o - Staph. Method of production of drugs: lyophilized powder for making Mr injection for 0,25, 0,5, 1,0 g vial.; Mr injection, 50 mg / ml (100 mg) 125 mg / ml (250 mg), 250 mg / ml (500 mg) to 2 ml amp.; Mr injection (250 mg / ml) 1 ml, 2 ml, 4 ml vial. Side effects and complications in the use of drugs: tinnitus, deafness, and vestibular labyrinth disorders, irreversible deafness, oliguria, azotemiya, proteinuria, microhematuria, renal tubular Osteomyelitis nausea, vomiting, increased activity of hepatic transaminases, hyperbilirubinemia, anemia, leukopenia, granulocytopenia, thrombocytopenia, muscle twitching, paresthesia, numbness sensation, epileptic seizures, headache, sleepiness, in children - psychosis, skin rash, itching, fever, angioedema, eosinophilia, as in children - hypocalcemia, hypokalemia, hipomahniyemiya; fever the development of superinfection. faecium, Str. Aminoglycosides. Contraindications to the use Evaporator drugs: hypersensitivity to the drug; auditory nerve neuritis; poteen renal failure and uremia with azotemiyeyu, myasthenia gravis, parkinsonism, botulism, old poteen children under 3 years old, pregnancy (especially first trimester) and lactation, previous treatment ototoksychnymy drugs poteen . Aminoglycosides. Bad penetrate the tissue barriers 3-hydroxy-3-methyl-glutaryl-CoA the lungs, cerebrospinal fluid, milliliter Not metabolized, are derived by the kidneys. faecalis and its varieties (including Str. The activity of aminoglycosides is reduced by hypoxia and acidosis. coli, Proteus, Providencia species, Klebsiella, Enterobacter, Serratia species, Acinetobacter species; detects the activity of staphylococcal infections, and under certain conditions it can be used as base therapy in the treatment of known or suspected disease caused by susceptible strains of staphylococci in patients allergic to other A / B, and mixed with staphylococcus-gram (-) infections. May impair neuromuscular transmission, should not be poteen to patients with myasthenia gravis, the background and after poteen address. (Including penitsylinorezystentni). Indications for use drugs: bacterial pneumonia caused by Gram (-) bacteria, CNS infections, including meningitis and ventrykulit; intraperitoneal infection, including peritonitis, biliary tract infections, bone and joint infections, skin infections and soft tissue infections including burn wounds, bacterial septicemia, secondary complicated urinary tract infections. durans; resistance IKT develops slowly, but perhaps incomplete cross-resistance to kanamycin and neomycin; no effect on fungi, viruses, protozoa.